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Peb Melanotan II yog ib qho khoom siv peptide uas muaj kev ntshiab siab, tsim los ntawm kev tsim khoom, tsim tawm raws li cov qauv tswj kev zoo. Ua ib qho tshuaj lom neeg tshawb fawb, nws yog siv rau kev tshawb fawb biomedical thiab pharmacological los tshawb txog lub luag haujlwm nyuaj ntawm melanocortin receptor signaling hauv daim tawv nqaij pigmentation, kev tswj kev ntshaw, kev coj cwj pwm sib deev, thiab kev sib npaug zog. Cov khoom no yog raunyob rau hauv vitrotsuas yog siv rau kev tshawb fawb xwb thiab tsis yog rau kev kuaj mob, kev kho mob, lossis kev siv rau tib neeg.
Kev piav qhia txog khoom
Peb Melanotan II yog ib qho khoom siv peptide uas muaj kev ntshiab siab, tsim los ntawm kev tsim khoom, tsim tawm raws li cov qauv tswj kev zoo. Ua ib qho tshuaj lom neeg tshawb fawb, nws yog siv rau kev tshawb fawb biomedical thiab pharmacological los tshawb txog lub luag haujlwm nyuaj ntawm melanocortin receptor signaling hauv daim tawv nqaij pigmentation, kev tswj kev ntshaw, kev coj cwj pwm sib deev, thiab kev sib npaug zog. Cov khoom no yog rau nyob rau hauv vitrotsuas yog siv rau kev tshawb fawb xwb thiab tsis yog rau kev kuaj mob, kev kho mob, lossis kev siv rau tib neeg.
Cov cwj pwm
| Lub Npe Lus Askiv | Melanotan II | Qhov Ceev | / |
| CAS TSIS MUAJ | 121062-08-6 | Cov Ntawv Qhia Txog Kev Hloov Pauv | / |
| Cov Qauv Molecular | C₅₀H₆₈N₁₄O₁₀ | Kev Khaws Cia | -20°C lossis qis dua, ziab, tiv thaiv ntawm lub teeb |
| Mol. wt. | 1024.2 g/mol | Kev yaj tau | Yaj hauv dej, dilute acetic acid |
| EINECS No. | / | Daim Ntawv | Hmoov Lyophilized |
| MDL No. | MFCD00237494 | Xim | Dawb rau cov hmoov dawb dawb |
| Cov Ntsiab Lus Yaj | / | Tus nqi PH | / |
| Kev Ruaj Ntseg | Ruaj khov thaum khaws cia qhuav thiab khov ntawm -20°C lossis qis dua. Tsis txhob rov ua dua cov voj voog khov-thaw. Cov tshuaj uas tau sib tov lawm yuav tsum siv tam sim ntawd lossis khaws cia ntawm -20°C rau kev siv luv luv. | ||
Cov Khoom Noj Muaj Quav
Ua ib qho peptide tsim uas huv si heev, nws cov khoom sib xyaw tsuas yog txhais los ntawm nws cov amino acid sib lawv liag. Nws tsis muaj rog, carbohydrates, lossis lwm yam macro-nutrients. Cov khoom no tsuas yog rau kev tshawb fawb siv xwb.
Ua ib qho analog ntawm alpha-melanocyte-stimulating hormone (ib-MSH), Melanotan II ua kom lub melanocortin-1 receptor (MC1R) ua haujlwm tau zoo, yog li ntawd txhawb kev tsim thiab faib cov melanin hauv daim tawv nqaij. Kev tshawb fawb qhia tau tias nws tuaj yeem ua rau daim tawv nqaij tanning yam tsis muaj UV thiab tej zaum yuav muab qee qhov kev tiv thaiv tiv thaiv ultraviolet radiation.
Los ntawm kev ua kom cov melanocortin receptors nyob rau hauv lub paj hlwb hauv nruab nrab (tshwj xeeb tshaj yog MC4R), Melanotan II tau qhia txog cov teebmeem pro-sexual ("erectogenic") thiab muaj peev xwm txo qhov kev ntshaw hauv kev tshawb fawb txog tsiaj txhu.
Kev tshawb fawb ua ntej qhia tau hais tias kev ua kom lub cev melanocortin ua haujlwm tau zoo yuav hloov pauv kev siv zog thiab kev ua kom cov piam thaj hauv lub cev, txawm hais tias cov txheej txheem thiab cov teebmeem tseem raug tshawb nrhiav.
Ua haujlwm ua ib qho cuab yeej tseem ceeb rau kev kawm txog melanocortin receptor (MC1R-MC5R) signaling, physiological functions, thiab lawv lub luag haujlwm hauv ntau yam mob xws li mob tawv nqaij, rog dhau, thiab kev ua haujlwm tsis zoo ntawm kev sib deev.
Siv los tshawb nrhiav lub peev xwm ntawm kev ua kom melanogenesis rau kev tiv thaiv kev puas tsuaj UV thiab los kawm txog pathophysiology ntawm cov teeb meem ntsig txog pigmentation.
Vim nws muaj zog heev rau kev siv tshuaj, nws tau siv dav hauv cov kev pab cuam tsim tshuaj thaum ntxov los ntsuas nws lub peev xwm hauv kev kho mob erectile dysfunction, poj niam tsis muaj zog sib deev, thiab ua tus neeg sawv cev tanning. (Thov nco ntsoov: Cov tshuaj no tsis tau pom zoo los ntawm cov koom haum tswj hwm tshuaj loj rau kev siv kho mob, thiab nws txoj kev siv tsis yog kho mob muaj kev pheej hmoo rau kev noj qab haus huv.)
Txog Peb
