Tshuaj Peptide

Eptifibatide GMP DMF Qib: Cov Khoom Siv Raw Siab Rau Kev Tshawb Fawb Txog Kab Mob Pharma

Eptifibatide yog ib hom tshuaj heptapeptide uas ua haujlwm ua ob qho tib si anticoagulant thiab antiplatelet agent. Tsim tawm raws li cov cai Good Manufacturing Practice (GMP) thiab txhawb nqa los ntawm Drug Master File (DMF), Eptifibatide ua haujlwm zoo rau glycoprotein IIb/IIIa receptor. Los ntawm kev thaiv tshwj xeeb no, nws tiv thaiv platelet aggregation, txo qhov kev pheej hmoo ntawm thrombotic events thaum lub sijhawm ua haujlwm ntawm lub plawv. Tus neeg sawv cev muaj zog no yog qhov tseem ceeb rau kev txhim kho cov txiaj ntsig ntawm tus neeg mob hauv kev cuam tshuam tseem ceeb ntawm lub plawv.

Tiv tauj peb

cov ntsiab lus ntawm cov khoom

piav qhia1

Kev piav qhia txog khoom

Eptifibatide GMP DMF qib yog cov peptide hluavtaws uas muaj qhov huv siab uas tsim tawm raws li cov qauv tsim tshuaj nruj. Nws xaiv khi rau platelet glycoprotein IIb / IIIa receptor, tiv thaiv tau zoo fibrinogen cross-linking thiab platelet aggregation. Cov khoom lag luam qhia tau tias muaj qhov huv zoo heev, ruaj khov, thiab sib xws ua ke, ua rau nws yog cov khoom xyaw tshuaj txhim khu kev qha rau kev kho mob plawv mob hnyav.

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Cov cwj pwm

Lub Npe Lus Askiv	Eptifibatide	Qhov Ceev
CAS TSIS MUAJ	148031-34-9	Kev Ruaj Ntseg	Ruaj khov hauv lub xeev lyophilized (kaw, -20 ℃ txog -80 ℃); tsis txhob rov ua dua cov voj voog khov-thaw, cov tshuaj oxidants muaj zog, thiab cov xwm txheej pH hnyav.
Cov Qauv Molecular	C₃₅H₄₉N₁₁O₉S₂	Kev Khaws Cia	Kaw, tiv taus lub teeb, thiab tiv taus dej noo; khaws cia ntawm -20 ℃ txog -80 ℃ hauv cov chaw ua raws li GMP
Mol.wt.	831.96	Kev yaj tau	Yooj yim yaj hauv dej (≥25 mg / mL ntawm 25 ℃), me ntsis yaj hauv methanol, tsis yaj hauv ether
EINECS No.	Tsis muaj	Daim Ntawv	Hmoov
MDL No.	MFCD00867577	Xim	Dawb rau dawb-dawb lyophilized hmoov
Qhov Kub Yaj	Decomposes saum toj no 220 ℃ (lyophilized daim ntawv)	Tus nqi pH	4.5-6.5 (0.5% kua dej)

Cov Txiaj Ntsig Tseem Ceeb rau Kev Noj Qab Haus Huv

Cov Txheej Txheem Ua Haujlwm

Kev Ua Haujlwm Zoo ntawm Antiplatelet

Muab kev txwv sai thiab thim rov qab ntawm platelet aggregation los ntawm kev thaiv tshwj xeeb fibrinogen khi rau GP IIb / IIIa receptors.

Kev Noj Qab Haus Huv Ntawm Lub Plawv Thiab Lub Cev2

Kev Tswj Xyuas Kab Mob Hlwb Acute Coronary Syndrome

Txo cov teeb meem thrombotic hauv cov neeg mob uas muaj cov kab mob coronary mob hnyav, suav nrog angina tsis ruaj khov thiab non-ST-elevation myocardial infarction.

Kev Txhawb Nqa PCI

Txo cov teeb meem ischemic thaum lub sijhawm thiab tom qab percutaneous coronary interventions (PCI) los ntawm kev tiv thaiv cov platelet-mediated thrombosis.

Cov ntawv thov

Kev Kho Mob Hnyav hauv Tsev Kho Mob

Ib feem tseem ceeb hauv cov txheej txheem kho mob plawv thaum muaj xwm txheej ceev rau kev tiv thaiv cov xwm txheej thrombotic mob hnyav.

Kev Noj Qab Haus Huv ntawm Lub Plawv thiab Lub Cev

Kev Kho Mob Plawv

API tseem ceeb rau cov tshuaj txhaj uas siv rau hauv kev tswj hwm mob plawv mob hnyav thiab PCI adjunctive therapy.

Kev Tshawb Fawb Txog Kev Tiv Thaiv Kab Mob

Tus qauv siv rau kev tsim cov tshuaj antiplatelet tshiab thiab kev kho mob ua ke antithrombotic.

Kev Tswj Xyuas Zoo

Peb ua raws li cov qauv kev tswj xyuas zoo kom ntseeg tau tias peb cov Eptifibatide ua tau raws li cov qauv siab tshaj plaws ntawm kev huv thiab kev ua haujlwm zoo. Txhua pawg raug kuaj xyuas kom paub tseeb tias muaj cov tshuaj nquag thiab los tshuaj xyuas cov khoom tsis huv.

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Txog Peb

Shaanxi Bieyouth Biotech Co., Ltd. zoo siab los muab Eptifibatide, ib qho tshuaj ntxiv tshiab rau cov neeg uas xav txhim kho lawv txoj kev noj qab haus huv ntawm lub cev thiab tiv thaiv kev puas tsuaj ntawm lub sijhawm. Los ntawm kev koom ua ke peb cov Eptifibatide rau hauv koj txoj kev noj qab haus huv, koj tab tom ua ib kauj ruam tseem ceeb los tiv thaiv koj lub cev cov hlwb thiab txhawb kom muaj lub neej ntev dua thiab noj qab haus huv dua. Paub txog lub zog ntawm cov tshuaj antioxidant zoo no thiab txais yuav cov txiaj ntsig ntawm Eptifibatide rau koj txoj kev noj qab haus huv.